IkappaB-epsilon Antikörper (pSer22)

Produktnummer ABIN7222756

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch IkappaB-epsilon in IF, ELISA, WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für IkappaB-epsilon Antikörper (pSer22) (ABIN7222756)

Target: IkappaB-epsilon

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IkappaB-epsilon Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IkappaB-epsilon Antikörper

Bindungsspezifität: pSer22

Verwendungszweck: IκB-ε (phospho Ser22) Polyclonal Antibody

Spezifität: Phospho-IκB-ε (S22) Polyclonal Antibody detects endogenous levels of IκB-ε protein only when phosphorylated at S22.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human IkappaB-epsilon Phospho-Ser22

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu IkappaB-epsilon

Target: IkappaB-epsilon

Hintergrund: Rabbit Anti-IκB-ε (phospho Ser22) Polyclonal Antibody,NFKBIE, IKBE, NF-kappa-B inhibitor epsilon, NF-kappa-BIE, I-kappa-B-epsilon, IkB-E, IkB-epsilon, IkappaBepsilon,The protein encoded by NFKBIE binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.,NF-kappa-B inhibitor epsilon

Molekulargewicht: observerd band 38kDa

Gen-ID: 4794

UniProt: O00221