HTRA2 Antikörper (pSer142)

Produktnummer ABIN7221152

Der Kaninchen Polyklonal Anti-HTRA2 Antikörper wurde für ELISA und IHC (p) validiert. Er ist geeignet, HTRA2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für HTRA2 Antikörper (pSer142) (ABIN7221152)

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HTRA2 Antikörper

Bindungsspezifität: pSer142

Verwendungszweck: HtrA2 (phospho Ser142) Polyclonal Antibody

Spezifität: Phospho-HtrA2 (S142) Polyclonal Antibody detects endogenous levels of HtrA2 protein only when phosphorylated at S142.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human HtrA2 Phospho-Ser142

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HtrA2

Hintergrund: Rabbit Anti-HtrA2 (phospho Ser142) Polyclonal Antibody,HTRA2, OMI, PRSS25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI,HTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.,Serine protease HTRA2 mitochondrial

Gen-ID: 27429

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity