HUNK Antikörper (AA 220-300)

Produktnummer ABIN7221478

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HUNK in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für HUNK Antikörper (AA 220-300) (ABIN7221478)

Target: HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HUNK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HUNK Antikörper

Bindungsspezifität: AA 220-300

Verwendungszweck: HUNK Polyclonal Antibody

Spezifität: HUNK Polyclonal Antibody detects endogenous levels of HUNK protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human HUNK at AA range: 220-300

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu HUNK

Target: HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))

Andere Bezeichnung: HUNK

Hintergrund: Rabbit Anti-HUNK Polyclonal Antibody,HUNK, MAKV, Hormonally up-regulated neu tumor-associated kinase, B19, Serine/threonine-protein kinase MAK-V,The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50 % of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha and CAB39.,Hormonally up-regulated neu tumor-associated kinase

Molekulargewicht: observerd band 75kDa

Gen-ID: 30811

UniProt: P57058