HJURP Antikörper (AA 80-160)

Produktnummer ABIN7228926

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HJURP in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für HJURP Antikörper (AA 80-160) (ABIN7228926)

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HJURP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HJURP Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: Rabbit Anti-HJURP Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of HJURP protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HJURP protein at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HJURP

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Andere Bezeichnung: HJURP

Hintergrund: Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9HJURP (Holliday Junction Recognition Protein) is a Protein Coding gene. Diseases associated with HJURP include Fibrillary Astrocytoma. Among its related pathways are DNA Damage and Chromosome Maintenance. Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.

Molekulargewicht: 82kD

Gen-ID: 55355

UniProt: Q8NCD3