HRG Antikörper

Produktnummer ABIN7228966

Der Kaninchen Polyklonal anti-HRG Antikörper wird verwendet zum Nachweis von HRG in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für HRG Antikörper (ABIN7228966)

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HRG Antikörper

Verwendungszweck: Rabbit Anti-HRG Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of HRG protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HRG protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HRG

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Andere Bezeichnung: HRG

Hintergrund: Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRGThis histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. Histidine Rich Glycoprotein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Molekulargewicht: 57kD

Gen-ID: 3273

UniProt: P04196