ATRX Antikörper (AA 80-160)

Produktnummer ABIN7223298

Der Kaninchen Polyklonal Anti-ATRX Antikörper wurde für ELISA und IF validiert. Er ist geeignet, ATRX in Proben von Human und Maus zu detektieren.

Kurzübersicht für ATRX Antikörper (AA 80-160) (ABIN7223298)

Target: ATRX (helicase 2, X-linked (ATRX))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATRX Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-ATRX Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: ATRX Polyclonal Antibody

Spezifität: ATRX Polyclonal Antibody detects endogenous levels of ATRX protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human ATRX at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ATRX

Target: ATRX (helicase 2, X-linked (ATRX))

Andere Bezeichnung: ATRX

Hintergrund: Rabbit Anti-ATRX Polyclonal Antibody,ATRX, RAD54L, XH2, Transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX,The protein encoded by ATRX (ATRX, chromatin remodeler) contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in ATRX are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.,Transcriptional regulator ATRX

Gen-ID: 546

UniProt: P46100