GDF5 Antikörper (Internal Region)

Produktnummer ABIN7218140

Dieser Anti-GDF5 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von GDF5 in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für GDF5 Antikörper (Internal Region) (ABIN7218140)

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GDF5 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: GDF-5 Polyclonal Antibody

Spezifität: GDF-5 Polyclonal Antibody detects endogenous levels of GDF-5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GDF-5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: GDF-5

Hintergrund: Rabbit Anti-GDF-5 Polyclonal Antibody,GDF5, CDMP1, Growth/differentiation factor 5, GDF-5, Cartilage-derived morphogenetic protein 1, CDMP-1, Radotermin,GDF5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Growth/differentiation factor 5 regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.,Growth

Molekulargewicht: observerd band 55kDa

Gen-ID: 8200

UniProt: P43026