GDF10 Antikörper

Produktnummer ABIN7227490

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GDF10 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für GDF10 Antikörper (ABIN7227490)

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GDF10 Antikörper

Verwendungszweck: Rabbit Anti-BMP3B Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of BMP3B protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human BMP3B protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GDF10

Target: GDF10 (Growth Differentiation Factor 10 (GDF10))

Andere Bezeichnung: BMP3B

Hintergrund: Growth/differentiation factor 10, GDF-10, Bone morphogenetic protein 3B, BMP-3B, Bone-inducing protein, BIPGDF10 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of GDF10 is associated with oral cancer.

Molekulargewicht: 52kD

Gen-ID: 2662

UniProt: P55107