GAS2 Antikörper

Produktnummer ABIN7228616

Der Kaninchen Polyklonal anti-GAS2 Antikörper (ABIN7228616) detektiert spezifisch GAS2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für GAS2 Antikörper (ABIN7228616)

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GAS2 Antikörper

Verwendungszweck: Rabbit Anti-GAS2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of GAS2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GAS2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GAS2

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Andere Bezeichnung: GAS2

Hintergrund: Growth arrest-specific protein 2, GAS-2The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants. GAS2 (Growth Arrest Specific 2) is a Protein Coding gene. Diseases associated with GAS2 include Gnathodiaphyseal Dysplasia. Among its related pathways are p70S6K Signaling and Akt Signaling. An important paralog of this gene is GAS2L3.

Molekulargewicht: 34kD

Gen-ID: 2620

UniProt: O43903

Pathways: Caspase Kaskade in der Apoptose