GRAP2 Antikörper (AA 90-170)

Produktnummer ABIN7214992

Der Kaninchen Polyklonal anti-GRAP2 Antikörper wird verwendet zum Nachweis von GRAP2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für GRAP2 Antikörper (AA 90-170) (ABIN7214992)

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GRAP2 Antikörper

Bindungsspezifität: AA 90-170

Verwendungszweck: Rabbit Anti-Gads Polyclonal Antibody

Spezifität: Gads Polyclonal Antibody detects endogenous levels of Gads protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Gads at AA range: 90-170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GRAP2

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Andere Bezeichnung: Gads

Hintergrund: GRAP2, GADS, GRB2L, GRID, GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpGRAP2 encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. GRB2-related adapter protein 2 interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht: 38kD

Gen-ID: 9402

UniProt: O75791

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung