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GNRHR Antikörper (AA 10-90)

Der Kaninchen Polyklonal Anti-GNRHR Antikörper wurde für WB, IF und ELISA validiert. Er ist geeignet, GNRHR in Proben von Human und Maus zu detektieren.
Produktnummer ABIN7221168

Kurzübersicht für GNRHR Antikörper (AA 10-90) (ABIN7221168)

Target

Alle GNRHR Antikörper anzeigen
GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reaktivität

  • 70
  • 18
  • 12
  • 2
  • 1
Human, Maus

Wirt

  • 42
  • 31
  • 1
Kaninchen

Klonalität

  • 42
  • 32
Polyklonal

Konjugat

  • 37
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GNRHR Antikörper ist unkonjugiert

Applikation

  • 28
  • 27
  • 26
  • 19
  • 11
  • 9
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA
  • Bindungsspezifität

    • 27
    • 26
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-90

    Verwendungszweck

    GnRH-R Polyclonal Antibody

    Spezifität

    GnRH-R Polyclonal Antibody detects endogenous levels of GnRH-R protein.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogen

    Synthesized peptide derived from the Internal region of human GnRH-R at AA range: 10-90

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    Kommentare

    Primary Antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target

    GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

    Andere Bezeichnung

    GnRH-R

    Hintergrund

    Rabbit Anti-GnRH-R Polyclonal Antibody,GNRHR, GRHR, Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R,GNRHR encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.,Gonadotropin-releasing hormone receptor

    Molekulargewicht

    observerd band 37kDa

    Gen-ID

    2798

    UniProt

    P30968
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