GP6 Antikörper

Produktnummer ABIN7228766

Der Kaninchen Polyklonal anti-GP6 Antikörper (ABIN7228766) detektiert spezifisch GP6 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für GP6 Antikörper (ABIN7228766)

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GP6 Antikörper

Verwendungszweck: Rabbit Anti-GPVI Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of GPVI protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GPVI protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GP6

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Andere Bezeichnung: GPVI

Hintergrund: Platelet glycoprotein VI, GPVI, Glycoprotein 6GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. Glycoprotein VI Platelet is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht: 55kD

Gen-ID: 51206

UniProt: Q9HCN6