Glutaredoxin 1 Antikörper (AA 40-120)

Produktnummer ABIN7228674

Dieser Anti-Glutaredoxin 1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Glutaredoxin 1 in WB und ELISA. Geeignet für Human.

Kurzübersicht für Glutaredoxin 1 Antikörper (AA 40-120) (ABIN7228674)

Target: Glutaredoxin 1 (GRX1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaredoxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Glutaredoxin 1 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: GLRX1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of GLRX1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human GLRX1 protein at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Andere Bezeichnung: GLRX1

Hintergrund: Rabbit Anti-GLRX1 Polyclonal Antibody,Glutaredoxin-1, Thioltransferase-1, TTase-1,GLRX encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.,GLRX1

Molekulargewicht: observerd band 11kDa

Gen-ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis