GLP1R Antikörper (AA 80-160)

Produktnummer ABIN7215072

Der Kaninchen-Polyklonal Anti-GLP1R-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet zum Nachweis von GLP1R in Proben aus Human und Maus. }

Kurzübersicht für GLP1R Antikörper (AA 80-160) (ABIN7215072)

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLP1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-GLP1R Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: GLP-1R Polyclonal Antibody

Spezifität: GLP-1R Polyclonal Antibody detects endogenous levels of GLP-1R protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GLP-1R at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu GLP1R

Target: GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))

Andere Bezeichnung: GLP-1R

Hintergrund: Rabbit Anti-GLP-1R Polyclonal Antibody,GLP1R, Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R,GLP1R encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. Glucagon-like peptide 1 receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. Glucagon-like peptide 1 receptor is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.,Glucagon-like peptide 1 receptor

Molekulargewicht: observerd band 53kDa

Gen-ID: 2740

UniProt: P43220

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour