Kurzübersicht für GGT4 HC (AA 400-480), (Cleaved-Thr472) Antikörper (ABIN7221058)
Target
GGT4 HC
Reaktivität
Human, Maus, Ratte
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Unkonjugiert
Applikation
ELISA, Western Blotting (WB)
Bindungsspezifität
AA 400-480, Cleaved-Thr472
Verwendungszweck
Rabbit Anti-Cleaved-GGT4 HC (T472) Polyclonal Antibody
Spezifität
Cleaved-GGT4 HC (T472) Polyclonal Antibody detects endogenous levels of fragment of activated GGT4 HC protein resulting from cleavage adjacent to T472.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Synthesized peptide derived from the Internal region of human GGT4 HC at AA range: 400-480
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
GGT4 HC
Hintergrund
GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, GGT 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7GGT7 is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The gamma-glutamyltransferase 7 encoded by GGT7 consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis.