GCSc-gamma (Internal Region) Antikörper

Produktnummer ABIN7215036

Der Kaninchen Polyklonal anti-GCSc-gamma Antikörper wird verwendet zum Nachweis von GCSc-gamma in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA und WB.

Kurzübersicht für GCSc-gamma (Internal Region) Antikörper (ABIN7215036)

Target: GCSc-gamma

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: Internal Region

Verwendungszweck: GCSc-γ Polyclonal Antibody

Spezifität: GCSc-γ Polyclonal Antibody detects endogenous levels of GCSc-γ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GCSc-gamma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: GCSc-gamma

Hintergrund: Rabbit Anti-GCSc-γ Polyclonal Antibody,GCLC, GLCL, GLCLC, Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase,Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate--cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at GCLC have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.,Glutamate--cysteine ligase catalytic subunit

Molekulargewicht: observerd band 73kDa

Gen-ID: 2729

UniProt: P48506