GALR2 Antikörper (AA 180-260)

Produktnummer ABIN7225664

Der Kaninchen Polyklonal Anti-GALR2 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, GALR2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GALR2 Antikörper (AA 180-260) (ABIN7225664)

Target: GALR2 (Galanin Receptor 2 (GALR2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GALR2 Antikörper

Bindungsspezifität: AA 180-260

Verwendungszweck: GALR2 Polyclonal Antibody

Spezifität: GALR2 Polyclonal Antibody detects endogenous levels of GALR2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GALR2 at AA range: 180-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu GALR2

Target: GALR2 (Galanin Receptor 2 (GALR2))

Andere Bezeichnung: GALR2

Hintergrund: Rabbit Anti-GALR2 Polyclonal Antibody,GALR2, GALNR2, Galanin receptor type 2, GAL2-R, GALR-2,Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.,Galanin receptor type 2

Molekulargewicht: observerd band 42kDa

Gen-ID: 8811

UniProt: O43603

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour