GABRD Antikörper (AA 110-190)

Produktnummer ABIN7220892

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GABRD in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für GABRD Antikörper (AA 110-190) (ABIN7220892)

Target: GABRD (GABA A Receptor delta (GABRD))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-GABRD Antikörper

Bindungsspezifität: AA 110-190

Verwendungszweck: Rabbit Anti-GABAA Rδ Polyclonal Antibody

Spezifität: GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GABAA range: Rdelta at AA range: 110-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Andere Bezeichnung: GABAA Rdelta

Hintergrund: GABRD, Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit deltaGamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. GABRD encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.

Molekulargewicht: 51kD

Gen-ID: 2563

UniProt: O14764