MRGPRX2 Antikörper (AA 250-330)

Produktnummer ABIN7229756

Dieser Anti-MRGPRX2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MRGPRX2 in ELISA und WB. Geeignet für Human und Maus.

Kurzübersicht für MRGPRX2 Antikörper (AA 250-330) (ABIN7229756)

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-MRGPRX2 Antikörper

Bindungsspezifität: AA 250-330

Verwendungszweck: MRGX2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MRGX2 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MRGX2 protein at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Andere Bezeichnung: MRGX2

Hintergrund: Rabbit Anti-MRGX2 Polyclonal Antibody,Mas-related G-protein coupled receptor member X2,Mast cell-specific receptor for basic secretagogues, i.e. Cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed: 25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.,MRGX2

Molekulargewicht: observerd band 36kDa

Gen-ID: 117194

UniProt: Q96LB1