GPS2 Antikörper (AA 30-110)

Produktnummer ABIN7221282

Der Kaninchen Polyklonal anti-GPS2 Antikörper (ABIN7221282) detektiert spezifisch GPS2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GPS2 Antikörper (AA 30-110) (ABIN7221282)

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GPS2 Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: GPS2 Polyclonal Antibody

Spezifität: GPS2 Polyclonal Antibody detects endogenous levels of GPS2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human GPS2 at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu GPS2

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Andere Bezeichnung: GPS2

Hintergrund: Rabbit Anti-GPS2 Polyclonal Antibody,GPS2, G protein pathway suppressor 2, GPS-2,GPS2 encodes G protein pathway suppressor 2 involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.,G protein pathway suppressor 2

Molekulargewicht: observerd band 40kDa

Gen-ID: 2874

UniProt: Q13227