GFM2 Antikörper (AA 410-490)

Produktnummer ABIN7225406

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GFM2 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für GFM2 Antikörper (AA 410-490) (ABIN7225406)

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GFM2 Antikörper

Bindungsspezifität: AA 410-490

Verwendungszweck: Rabbit Anti-EF-G2 Polyclonal Antibody

Spezifität: EF-G2 Polyclonal Antibody detects endogenous levels of EF-G2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human EF-G2 at AA range: 410-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Andere Bezeichnung: EF-G2

Hintergrund: GFM2, EFG2, MSTP027, Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2, Elongation factor G2, hEFG2Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 (G elongation factor mitochondrial 2) encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 87kD

Gen-ID: 84340

UniProt: Q969S9

Pathways: Ribonucleoprotein Complex Subunit Organization