Fukutin Antikörper (AA 111-160)

Produktnummer ABIN7228550

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Fukutin in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Fukutin Antikörper (AA 111-160) (ABIN7228550)

Target: Fukutin (FKTN)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fukutin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Fukutin Antikörper

Bindungsspezifität: AA 111-160

Verwendungszweck: Rabbit Anti-FKTN Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FKTN protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FKTN protein at AA range: 111-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Fukutin

Target: Fukutin (FKTN)

Andere Bezeichnung: FKTN

Hintergrund: Fukutin, Fukuyama-type congenital muscular dystrophy proteinThe protein encoded by FKTN is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in FKTN are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for FKTN.

Molekulargewicht: 50kD

Gen-ID: 2218

UniProt: O75072

Pathways: Regulation of Carbohydrate Metabolic Process