FRAT1 Antikörper (AA 130-210)

Produktnummer ABIN7228590

Der Kaninchen Polyklonal anti-FRAT1 Antikörper wird verwendet zum Nachweis von FRAT1 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für FRAT1 Antikörper (AA 130-210) (ABIN7228590)

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FRAT1 Antikörper

Bindungsspezifität: AA 130-210

Verwendungszweck: Rabbit Anti-FRAT1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FRAT1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FRAT1 protein at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FRAT1

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Andere Bezeichnung: FRAT1

Hintergrund: Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1FRAT1 (FRAT1, WNT Signaling Pathway Regulator) is a Protein Coding gene. Among its related pathways are Endometrial cancer and Signaling by Wnt. An important paralog of this gene is FRAT2. The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.

Molekulargewicht: 30kD

Gen-ID: 10023

UniProt: Q92837