FOXC1 Antikörper (AA 120-200)

Produktnummer ABIN7220590

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FOXC1 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für FOXC1 Antikörper (AA 120-200) (ABIN7220590)

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-FOXC1 Antikörper

Bindungsspezifität: AA 120-200

Verwendungszweck: Rabbit Anti-FoxC1/2 Polyclonal Antibody

Spezifität: FoxC1/2 Polyclonal Antibody detects endogenous levels of FoxC1/2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human FoxC1/2 at AA range: 120-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Andere Bezeichnung: FoxC1/2

Hintergrund: FOXC1, FKHL7, FREAC3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FREAC-3, FOXC2, FKHL14, MFH1, Forkhead box protein C2, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1,FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.

Molekulargewicht: 57kD

Gen-ID: 2296, 2303

UniProt: Q12948, Q99958

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process