FIL1L Antikörper (AA 30-110)

Produktnummer ABIN7214602

Der Kaninchen Polyklonal Anti-FIL1L Antikörper wurde für ELISA und WB validiert. Er ist geeignet, FIL1L in Proben von Human und Maus zu detektieren.

Kurzübersicht für FIL1L Antikörper (AA 30-110) (ABIN7214602)

Target: FIL1L (FILIP1L) (Filamin A Interacting Protein 1-Like (FILIP1L))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIL1L Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-FIL1L Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: DOC-1 Polyclonal Antibody

Spezifität: DOC-1 Polyclonal Antibody detects endogenous levels of DOC-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human DOC-1 at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FIL1L

Target: FIL1L (FILIP1L) (Filamin A Interacting Protein 1-Like (FILIP1L))

Andere Bezeichnung: DOC-1

Hintergrund: Rabbit Anti-DOC-1 Polyclonal Antibody,CDK2AP1, CDKAP1, DOC1, Cyclin-dependent kinase 2-associated protein 1, CDK2-associated protein 1, Deleted in oral cancer 1, DOC-1, Putative oral cancer suppressor,Cyclin dependent kinase 2 associated protein 1encoded by CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,Cyclin-dependent kinase 2-associated protein 1

Molekulargewicht: observerd band 20kDa

Gen-ID: 8099

UniProt: O14519