FGFR1/FGFR2 Antikörper (pTyr463, pTyr466)

Produktnummer ABIN7220526

Dieser Anti-FGFR1/FGFR2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FGFR1/FGFR2 in WB und ELISA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für FGFR1/FGFR2 Antikörper (pTyr463, pTyr466) (ABIN7220526)

Target: FGFR1/FGFR2 (FGFR1, FGFR2)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFR1/FGFR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FGFR1/FGFR2 Antikörper

Bindungsspezifität: pTyr463, pTyr466

Verwendungszweck: Flg/Bek (phospho Tyr463/466) Polyclonal Antibody

Spezifität: Phospho-Flg/Bek (Y463/466) Polyclonal Antibody detects endogenous levels of Flg/Bek protein only when phosphorylated at Y463/466.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Flg/Bek Phospho-Tyr463/466

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FGFR1/FGFR2

Target: FGFR1/FGFR2 (FGFR1, FGFR2)

Andere Bezeichnung: Flg/Bek

Hintergrund: Rabbit Anti-Flg/Bek (phospho Tyr463/466) Polyclonal Antibody,FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, FGFR-1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD antigen CD331, FGFR2, BE,The fibroblast growth factor receptor 1 encoded by FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.,Basic fibroblast growth factor receptor 1

Molekulargewicht: observerd band 120kDa

Gen-ID: 2260, 2263