FARP2 Antikörper (AA 300-380)

Produktnummer ABIN7214904

Dieser Anti-FARP2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FARP2 in ELISA, WB und IF. Geeignet für Human und Maus.

Kurzübersicht für FARP2 Antikörper (AA 300-380) (ABIN7214904)

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FARP2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-FARP2 Antikörper

Bindungsspezifität: AA 300-380

Verwendungszweck: FIR Polyclonal Antibody

Spezifität: FIR Polyclonal Antibody detects endogenous levels of FIR protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human FIR at AA range: 300-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FARP2

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Andere Bezeichnung: FIR

Hintergrund: Rabbit Anti-FIR Polyclonal Antibody,FARP2, KIAA0793, PLEKHC3, FERM, RhoGEF and pleckstrin domain-containing protein 2, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3,FARP2 is a Protein Coding gene. FERM RhoGEF and pleckstrin domain-containing protein 2 functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion. Diseases associated with FARP2 include verheij syndrome and aarskog-scott syndrome. Among its related pathways are Developmental Biology and Adherens junction. GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and Rac guanyl-nucleotide exchange factor activity. An important paralog of this gene is FRMD3.,FERM RhoGEF and pleckstrin domain-containing protein 2

Molekulargewicht: observerd band 119kDa

Gen-ID: 9855

UniProt: O94887