SUPT16H Antikörper (AA 910-990)

Produktnummer ABIN7217092

Der Kaninchen Polyklonal anti-SUPT16H Antikörper wird verwendet zum Nachweis von SUPT16H in Proben von Human und Maus. Er wurde validiert für ELISA, WB, IHC und IF.

Kurzübersicht für SUPT16H Antikörper (AA 910-990) (ABIN7217092)

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUPT16H Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SUPT16H Antikörper

Bindungsspezifität: AA 910-990

Verwendungszweck: Rabbit Anti-SPT16 Polyclonal Antibody

Spezifität: SPT16 Polyclonal Antibody detects endogenous levels of SPT16 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human SPT16 at AA range: 910-990

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SUPT16H

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Andere Bezeichnung: SPT16

Hintergrund: SUPT16H, FACT140, FACTP140, FACT complex subunit SPT16, Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACTp140, Facilitates chromatin transcription complex subunit SPT16, hSPT16Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, this gene encodes the 140 kDa subunit.

Molekulargewicht: 119kD

Gen-ID: 11198

UniProt: Q9Y5B9

Pathways: Chromatin Binding