ERLIN1/2 Antikörper (AA 31-80)

Produktnummer ABIN7226896

Der Kaninchen Polyklonal Anti-ERLIN1/2 Antikörper wurde für ELISA und WB validiert. Er ist geeignet, ERLIN1/2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ERLIN1/2 Antikörper (AA 31-80) (ABIN7226896)

Target: ERLIN1/2

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERLIN1/2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-ERLIN1/2 Antikörper

Bindungsspezifität: AA 31-80

Verwendungszweck: ERLIN1/2 Polyclonal Antibody

Spezifität: ERLIN1/2 Polyclonal Antibody detects endogenous levels of ERLIN1/2.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from ERLIN1/2 at AA range: 31-80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ERLIN1/2

Target: ERLIN1/2

Hintergrund: Rabbit Anti-ERLIN1/2 Polyclonal Antibody,Erlin-1 and erlin-2 (SPFH1 and SPFH2) are SPFH domain-containing proteins that belong to the prohibitin family. The N-termal domain of erlin proteins contains ER-targeting sequences responsible for their translocation to the endoplasmic reticulum (ER). In the ER, erlin-1 and erlin-2 specifically associate with the detergent resistant lipid raft microdomain of the membrane. Erlin-1 may be involved in dentritic cell activation and erlin-2 has been shown to regulate the ER-associated degradation (ERAD) pathway by interacting with endogenous substrates and resulting in their polyubiquitination and degradation.,ERLIN1

Molekulargewicht: observerd band 40+42kDa