ERBB2IP Antikörper (pTyr1104)
Kurzübersicht für ERBB2IP Antikörper (pTyr1104) (ABIN7212952)
Target
Alle ERBB2IP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr1104
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Verwendungszweck
- Erbin (phospho Tyr1104) Polyclonal Antibody
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Spezifität
- Phospho-Erbin (Y1104) Polyclonal Antibody detects endogenous levels of Erbin protein only when phosphorylated at Y1104.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human Erbin Phospho-Tyr1104
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))
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Andere Bezeichnung
- Erbin
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Hintergrund
- Rabbit Anti-Erbin (phospho Tyr1104) Polyclonal Antibody,ERBB2IP, ERBIN, KIAA1225, LAP2, Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, Erbin,ERBIN is a member of the leucine-rich repeat and PDZ domain (LAP) family.Erbb2 interacting protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ERBIN.,Protein LAP2
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Molekulargewicht
- observerd band 172kDa
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Gen-ID
- 55914
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UniProt
- Q96RT1
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Pathways
- EGFR Signaling Pathway, Asymmetric Protein Localization
Target
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