EPH Receptor B1/2/3/4 Antikörper

Produktnummer ABIN7220304

Der Kaninchen Polyklonal anti-EPH Receptor B1/2/3/4 Antikörper wird verwendet zum Nachweis von EPH Receptor B1/2/3/4 in Proben von Human und Maus. Er wurde validiert für ELISA, WB, IHC und IF.

Kurzübersicht für EPH Receptor B1/2/3/4 Antikörper (ABIN7220304)

Target: EPH Receptor B1/2/3/4

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails

Verwendungszweck: Rabbit Anti-EphB1/2/3/4 Polyclonal Antibody

Spezifität: EphB1/2/3/4 Polyclonal Antibody detects endogenous levels of EphB1/2/3/4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human EphB1/2/3/4 around the non-phosphorylation site of Y600/602/614/596

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: EPH Receptor B1/2/3/4

Andere Bezeichnung: EphB1/2/3/4

Hintergrund: EPHB1, ELK, EPHT2, HEK6, NET, Ephrin type-B receptor 1, ELK, EPH tyrosine kinase 2, EPH-like kinase 6, EK6, hEK6, Neuronally-expressed EPH-related tyrosine kinase, NET, Tyrosine-protein kinase receptor EPH-2, EPHB2, DRT, EPHT3, EPTH3, ERK,Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EPH receptor B1 encoded by EPHB1 is a receptor for ephrin-B family members.

Molekulargewicht: 118kD

Gen-ID: 2047, 2048, 2049

UniProt: P54762, P29323, P54753, P54760