ECE2 Antikörper

Produktnummer ABIN7228344

Der Kaninchen Polyklonal anti-ECE2 Antikörper wird verwendet zum Nachweis von ECE2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für ECE2 Antikörper (ABIN7228344)

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ECE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ECE2 Antikörper

Verwendungszweck: Rabbit Anti-ECE2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ECE2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ECE2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ECE2

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Andere Bezeichnung: ECE2

Hintergrund: Endothelin-converting enzyme 2ECE2 (Endothelin Converting Enzyme 2) is a Protein Coding gene. Among its related pathways are A-beta Pathways: uptake and Degradation and Peptide ligand-binding receptors. GO annotations related to this gene include methyltransferase activity and metalloendopeptidase activity. An important paralog of this gene is ECE1. Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

Molekulargewicht: 97kD

Gen-ID: 9718

UniProt: O60344

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling