Endothelin 2 Antikörper

Produktnummer ABIN7228354

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Endothelin 2 in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Endothelin 2 Antikörper (ABIN7228354)

Target: Endothelin 2 (EDN2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin 2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-Endothelin 2 Antikörper

Verwendungszweck: Rabbit Anti-EDN2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of EDN2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human EDN2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Endothelin 2

Target: Endothelin 2 (EDN2)

Andere Bezeichnung: EDN2

Hintergrund: Endothelin-2, ET-2, Preproendothelin-2, PPET2EDN2 encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. Endothelin 2 is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 19kD

Gen-ID: 1907

UniProt: P20800

Pathways: Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones