ERC1 Antikörper

Produktnummer ABIN7230966

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ERC1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für ERC1 Antikörper (ABIN7230966)

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ERC1 Antikörper

Verwendungszweck: Rabbit Anti-RB6I2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RB6I2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RB6I2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ERC1

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Andere Bezeichnung: RB6I2

Hintergrund: ELKS/Rab6-interacting/CAST family member 1, ERC-1, Rab6-interacting protein 2The protein encoded by ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1) is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10,12)(q11,p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. ERC1 is a Protein Coding gene. Diseases associated with ERC1 include Differentiated Thyroid Carcinoma and Distal Monosomy 12P. Among its related pathways are NF-kappa B signaling pathway and Cytoskeletal Signaling.

Molekulargewicht: 122kD

Gen-ID: 23085

UniProt: Q8IUD2

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion