ELAC2 Antikörper (AA 130-210)

Produktnummer ABIN7224036

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch ELAC2 in ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ELAC2 Antikörper (AA 130-210) (ABIN7224036)

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELAC2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ELAC2 Antikörper

Bindungsspezifität: AA 130-210

Verwendungszweck: RNase Z2 Polyclonal Antibody

Spezifität: RNase Z2 Polyclonal Antibody detects endogenous levels of RNase Z2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human RNase Z2 at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ELAC2

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Andere Bezeichnung: RNase Z2

Hintergrund: Rabbit Anti-RNase Z2 Polyclonal Antibody,ELAC2, HPC2, Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, Heredity prostate cancer protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2,The protein encoded by ELAC2 (elaC ribonuclease Z 2) has a C-terminal domain with tRNA processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in ELAC2 result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for ELAC2.,Zinc phosphodiesterase ELAC protein 2

Gen-ID: 60528

UniProt: Q9BQ52