EKLF/CKLF/UKLF (AA 280-360) Antikörper

Produktnummer ABIN7214718

Der Kaninchen Polyklonal anti-EKLF/CKLF/UKLF Antikörper (ABIN7214718) detektiert spezifisch EKLF/CKLF/UKLF in ELISA, IF und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für EKLF/CKLF/UKLF (AA 280-360) Antikörper (ABIN7214718)

Target: EKLF/CKLF/UKLF

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 280-360

Verwendungszweck: Rabbit Anti-EKLF/CKLF/UKLF Polyclonal Antibody

Spezifität: EKLF/CKLF/UKLF Polyclonal Antibody detects endogenous levels of EKLF/CKLF/UKLF protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human EKLF/CKLF/UKLF at AA range: 280-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: EKLF/CKLF/UKLF

Hintergrund: KLF1, EKLF, Krueppel-like factor 1, Erythroid krueppel-like transcription factor, EKLF, KLF5, BTEB2, CKLF, IKLF, Krueppel-like factor 5, Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-boKLF1 encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in KLF1 result in the dominant In (Lu) blood phenotype.

Molekulargewicht: 38kD 20kD

Gen-ID: 10661, 688, 8609

UniProt: Q13351, Q13887, O75840