Dynamin 1 Antikörper (pSer774)

Produktnummer ABIN7220058

Der Kaninchen Polyklonal Anti-Dynamin 1 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, Dynamin 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Dynamin 1 Antikörper (pSer774) (ABIN7220058)

Target: Dynamin 1 (DNM1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Dynamin 1 Antikörper

Bindungsspezifität: pSer774

Verwendungszweck: Dynamin I (phospho Ser774) Polyclonal Antibody

Spezifität: Phospho-Dynamin I (S774) Polyclonal Antibody detects endogenous levels of Dynamin I protein only when phosphorylated at S774.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Dynamin I Phospho-Ser774

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Dynamin 1

Target: Dynamin 1 (DNM1)

Andere Bezeichnung: Dynamin I

Hintergrund: Rabbit Anti-Dynamin I (phospho Ser774) Polyclonal Antibody,DNM1, DNM, Dynamin-1,DNM1 encodes a member of the dynamin subfamily of GTP-binding proteins. Dynamin-1 possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.,Dynamin-1

Molekulargewicht: observerd band 97kDa

Gen-ID: 1759

UniProt: Q05193

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling