dTMP Kinase (AA 1-80) Antikörper

Produktnummer ABIN7214632

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch dTMP Kinase in ELISA, WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für dTMP Kinase (AA 1-80) Antikörper (ABIN7214632)

Target: dTMP Kinase

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: AA 1-80

Verwendungszweck: dTMP Kinase Polyclonal Antibody

Spezifität: DTMP Kinase Polyclonal Antibody detects endogenous levels of dTMP Kinase protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human dTMP Kinase at AA range: 1-80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: dTMP Kinase

Hintergrund: Rabbit Anti-dTMP Kinase Polyclonal Antibody,DTYMK, CDC8, TMPK, TYMK, Thymidylate kinase, dTMP kinase,Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.,Thymidylate kinase

Molekulargewicht: observerd band 22kDa

Gen-ID: 1841

UniProt: P23919