DOK2 Antikörper (pTyr299)

Produktnummer ABIN7212938

Der Kaninchen Polyklonal anti-DOK2 Antikörper wird verwendet zum Nachweis von DOK2 in Proben von Human, Maus und Affe. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für DOK2 Antikörper (pTyr299) (ABIN7212938)

Target: DOK2

Reaktivität: Human, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-DOK2 Antikörper

Bindungsspezifität: pTyr299

Verwendungszweck: Rabbit Anti-Dok-2 (phospho Tyr299) Polyclonal Antibody

Spezifität: Phospho-Dok-2 (Y299) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y299.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Dok-2 Phospho-Tyr299

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DOK2

Target: DOK2

Andere Bezeichnung: Dok-2

Hintergrund: DOK2, Docking protein 2, Downstream of tyrosine kinase 2, p56(dok-2)Docking protein 2 encoded by DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 2 binds p120 (RasGAP) from CML cells.

Molekulargewicht: 48kD

Gen-ID: 9046

UniProt: O60496