DOK7 Antikörper (AA 10-90)

Produktnummer ABIN7221244

Dieser Anti-DOK7 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von DOK7 in WB, ELISA, IF und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für DOK7 Antikörper (AA 10-90) (ABIN7221244)

Target: DOK7 (Docking Protein 7 (DOK7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DOK7 Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: Dok-7 Polyclonal Antibody

Spezifität: Dok-7 Polyclonal Antibody detects endogenous levels of Dok-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Dok-7 at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu DOK7

Target: DOK7 (Docking Protein 7 (DOK7))

Andere Bezeichnung: Dok-7

Hintergrund: Rabbit Anti-Dok-7 Polyclonal Antibody,DOK7, C4orf25, Protein Dok-7, Downstream of tyrosine kinase 7,The docking protein 7 encoded by DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in DOK7 are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.,Protein Dok-7

Molekulargewicht: observerd band 60kDa

Gen-ID: 285489

UniProt: Q18PE1

Pathways: Skeletal Muscle Fiber Development