DOK6 Antikörper (AA 80-160)

Produktnummer ABIN7214610

Der Kaninchen Polyklonal Anti-DOK6 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, DOK6 in Proben von Human und Maus zu detektieren.

Kurzübersicht für DOK6 Antikörper (AA 80-160) (ABIN7214610)

Target: DOK6 (Docking Protein 6 (DOK6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DOK6 Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: Dok-6 Polyclonal Antibody

Spezifität: Dok-6 Polyclonal Antibody detects endogenous levels of Dok-6 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Dok-6 at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu DOK6

Target: DOK6 (Docking Protein 6 (DOK6))

Andere Bezeichnung: Dok-6

Hintergrund: Rabbit Anti-Dok-6 Polyclonal Antibody,DOK6, DOK5L, Docking protein 6, Downstream of tyrosine kinase 6,The downstream of kinase family (Dok-1-7) are members of a class of "docking" proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.,Docking protein 6

Molekulargewicht: observerd band 43kDa

Gen-ID: 220164

UniProt: Q6PKX4