DLG3 Antikörper

Produktnummer ABIN7228236

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DLG3 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für DLG3 Antikörper (ABIN7228236)

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DLG3 Antikörper

Verwendungszweck: Rabbit Anti-DLG3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of DLG3 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DLG3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Andere Bezeichnung: DLG3

Hintergrund: Disks large homolog 3, Neuroendocrine-DLG, Synapse-associated protein 102, SAP-102, SAP102DLG3 (Discs Large MAGUK Scaffold Protein 3) is a Protein Coding gene. Diseases associated with DLG3 include X-Linked Non-Specific Intellectual Disability and Non-Syndromic Intellectual Disability. Among its related pathways are PI3K-Akt signaling pathway and Protein-protein interactions at synapses. DLG3 encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.

Molekulargewicht: 89kD

Gen-ID: 1741

UniProt: Q92796