DMGDH Antikörper (AA 790-870)

Produktnummer ABIN7214582

Der Kaninchen Polyklonal anti-DMGDH Antikörper wird verwendet zum Nachweis von DMGDH in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für DMGDH Antikörper (AA 790-870) (ABIN7214582)

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-DMGDH Antikörper

Bindungsspezifität: AA 790-870

Verwendungszweck: Rabbit Anti-DMGDH Polyclonal Antibody

Spezifität: DMGDH Polyclonal Antibody detects endogenous levels of DMGDH protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human DMGDH at AA range: 790-870

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DMGDH

Target: DMGDH (Dimethylglycine Dehydrogenase (DMGDH))

Andere Bezeichnung: DMGDH

Hintergrund: DMGDH, Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDHDMGDH encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme (dimethylglycine dehydrogenase) is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 97kD

Gen-ID: 29958

UniProt: Q9UI17