Desmoglein 3 Antikörper

Produktnummer ABIN7228308

Der Kaninchen Polyklonal anti-Desmoglein 3 Antikörper wird verwendet zum Nachweis von Desmoglein 3 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Desmoglein 3 Antikörper (ABIN7228308)

Target: Desmoglein 3 (DSG3)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmoglein 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Desmoglein 3 Antikörper

Verwendungszweck: Rabbit Anti-DSG3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of DSG3 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DSG3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Desmoglein 3

Target: Desmoglein 3 (DSG3)

Andere Bezeichnung: DSG3

Hintergrund: Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6DSG3 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG3 is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.

Molekulargewicht: 109kD

Gen-ID: 1830

UniProt: P32926