Desmoglein 3 Antikörper

Produktnummer ABIN7228308

Der Kaninchen Polyklonal Anti-Desmoglein 3 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Desmoglein 3 in Proben von Human zu detektieren.

Kurzübersicht für Desmoglein 3 Antikörper (ABIN7228308)

Target: Desmoglein 3 (DSG3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmoglein 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Desmoglein 3 Antikörper

Verwendungszweck: DSG3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of DSG3 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human DSG3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Desmoglein 3

Target: Desmoglein 3 (DSG3)

Andere Bezeichnung: DSG3

Hintergrund: Rabbit Anti-DSG3 Polyclonal Antibody,Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6,DSG3 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG3 is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.,DSG3

Molekulargewicht: observerd band 109kDa

Gen-ID: 1830

UniProt: P32926