Desmoglein 2 Antikörper (AA 370-450)

Produktnummer ABIN7220094

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Desmoglein 2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Desmoglein 2 Antikörper (AA 370-450) (ABIN7220094)

Target: Desmoglein 2 (DSG2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmoglein 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Desmoglein 2 Antikörper

Bindungsspezifität: AA 370-450

Verwendungszweck: Rabbit Anti-Dsg2 Polyclonal Antibody

Spezifität: Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Dsg2 at AA range: 370-450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Desmoglein 2

Target: Desmoglein 2 (DSG2)

Andere Bezeichnung: Dsg2

Hintergrund: DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGCDSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Molekulargewicht: 140kD

Gen-ID: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization