BCAR1 Antikörper (pTyr410)

Produktnummer ABIN715991

Produktdetails anti-BCAR1 Antikörper

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Bindungsspezifität: pTyr410

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCAR1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Will recognize BCAR1(Tyr414) in mouse and BCAR1(Tyr508) in rat

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human BCAR1 around the phosphorylation site of Tyr410.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BCAR1

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Andere Bezeichnung: Bcar1 (BCAR1 Produkte)

Synonyme: CAS antikoerper, CAS1 antikoerper, CASS1 antikoerper, CRKAS antikoerper, P130Cas antikoerper, AI385681 antikoerper, Cas antikoerper, Crkas antikoerper, P130CAS antikoerper, MGC68466 antikoerper, cas antikoerper, p130cas antikoerper, BCAR1 antikoerper, fc17f11 antikoerper, wu:fc17f11 antikoerper, zgc:175192 antikoerper, BCAR1, Cas family scaffolding protein antikoerper, breast cancer anti-estrogen resistance 1 antikoerper, breast cancer anti-estrogen resistance 1 L homeolog antikoerper, breast cancer anti-estrogen resistance protein 1 antikoerper, BCAR1 antikoerper, Bcar1 antikoerper, bcar1.L antikoerper, bcar1 antikoerper, LOC100435586 antikoerper

Hintergrund:

Synonyms: CAS, CAS1, CASS1, CRKAS, P130Cas, Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, BCAR1

Background: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

Gen-ID: 9564

UniProt: P56945

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling