DHRS2 Antikörper (AA 80-160)

Produktnummer ABIN7214562

Dieser Anti-DHRS2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von DHRS2 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für DHRS2 Antikörper (AA 80-160) (ABIN7214562)

Target: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHRS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DHRS2 Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: DHRS2 Polyclonal Antibody

Spezifität: DHRS2 Polyclonal Antibody detects endogenous levels of DHRS2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human DHRS2 at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu DHRS2

Target: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Andere Bezeichnung: DHRS2

Hintergrund: Rabbit Anti-DHRS2 Polyclonal Antibody,DHRS2, Dehydrogenase/reductase SDR family member 2, Dicarbonyl reductase HEP27, Protein D,DHRS2 (dehydrogenase/reductase (SDR family) member 2), also known as SDR25C1 or HEP27, is a 258 amino acid protein that localizes to the nucleus and belongs to the short-chain dehydrogenase/reductase (SDR) family. Functioning as an NADPH-dependent dicarbonyl reductase, DHRS2 is thought to inhibit cell replication by either converting cortisone in cortisol, or by catalyzing the oxidation of androgen and estrogen. The gene encoding DHRS2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.,Dehydrogenase

Molekulargewicht: observerd band 27kDa

Gen-ID: 10202

UniProt: Q13268

Pathways: C21-Steroid Hormone Metabolic Process