DOCK11 Antikörper

Produktnummer ABIN7228270

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DOCK11 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für DOCK11 Antikörper (ABIN7228270)

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DOCK11 Antikörper

Verwendungszweck: Rabbit Anti-DOC11 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of DOC11 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DOC11 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DOCK11

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Andere Bezeichnung: DOC11

Hintergrund: Dedicator of cytokinesis protein 11, Dedicator of cytokinesis protein 11, ACG, Zizimin-2DOCK11 (Dedicator Of Cytokinesis 11) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and G-protein signaling_Regulation of CDC42 activity. Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42.

Molekulargewicht: 228kD

Gen-ID: 139818

UniProt: Q5JSL3