DIDO1 Antikörper (AA 130-210)

Produktnummer ABIN7214568

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DIDO1 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für DIDO1 Antikörper (AA 130-210) (ABIN7214568)

Target: DIDO1 (Death Inducer-Obliterator 1 (DIDO1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIDO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-DIDO1 Antikörper

Bindungsspezifität: AA 130-210

Verwendungszweck: Rabbit Anti-Dio-1 Polyclonal Antibody

Spezifität: Dio-1 Polyclonal Antibody detects endogenous levels of Dio-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Dio-1 at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DIDO1

Target: DIDO1 (Death Inducer-Obliterator 1 (DIDO1))

Andere Bezeichnung: Dio-1

Hintergrund: DIDO1, C20orf158, DATF1, KIAA0333, Death-inducer obliterator 1, DIO-1, hDido1, Death-associated transcription factor 1, DATF-1Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. DIDO1 is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for DIDO1, encoding multiple isoforms.

Molekulargewicht: 244kD

Gen-ID: 11083

UniProt: Q9BTC0

Pathways: Hormone Activity